Lysosomal Acid Lipase Deficiency (LAL-D) is a rare, inherited metabolic disorder resulting from inadequate activity of the lysosomal acid lipase enzyme. This enzyme is essential for the breakdown of cholesterol esters and triglycerides in cells. When its activity is compromised, lipids can build up in various organs, notably the liver, spleen, blood vessels, and gastrointestinal tract, leading to progressive and potentially life-threatening complications.